Characterizing Components of the Dictyostelium centrosome

نویسندگان

  • Christine Zoglmeier
  • Thomas Cremer
چکیده

Ehrenwörtliche Versicherung Hiermit versichere ich, dass ich die vorliegende Arbeit selbstständig und ohne unerlaubte Hilfsmittel angefertigt habe.associated protein and a permanent centrosomal resident involved in centrosome duplication. (DdCrp), the most divergent member of the centrin family, possesses only two EF-hands and dissociates from the centrosome during mitosis. Eur. (2000). Comparative structural, molecular and functional aspects of the Dictyostelium discoideum centrosome. durch die Deutsche Forschungsgemeinschaft.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cellular and Molecular Analysis of NDR and LATS Kinases in Dictyostelium

Ich versichere hiermit ehrenwörtlich, dass die vorgelegte Dissertation von mir selbständig und ohne unerlaubte Hilfe angefertigt ist. NdrA of Dictyostelium localizes to the centrosome and is required for efficient phagocytosis. Traffic, in press. cytokinesis in Dictyostelium discoideum. Dictyostelium discoideum by a SIN-related pathway. Eur. discoideum is regulated by a SIN-related pathway. of ...

متن کامل

A cDNA encoding a 224-kDa Dictyostelium discoideum

From an evolutionary perspective, the Dictyostelium centrosome is an intriguing organelle. Like its counterpart in yeast, the spindle pole body, it exhibits a compact, layered structure that lacks the centrioles typical of metazoan cells, but as in the latter, the core is surrounded by an electron-dense, amorphous matrix. With vertebrate centrosomes it shares a cytoplasmic localization in inter...

متن کامل

Rules of engagement: centrosome–nuclear connections in a closed mitotic system

The assembly of a functional mitotic spindle is essential for cell reproduction and requires a precise coordination between the nuclear cycle and the centrosome. This coordination is particularly prominent in organisms that undergo closed mitosis where centrosomes must not only respond to temporal signals, but also to spatial considerations, e.g. switching from the production of cytoplasmic mic...

متن کامل

Unusual centrosome cycle in Dictyostelium: correlation of dynamic behavior and structural changes.

Centrosome duplication and separation are of central importance for cell division. Here we provide a detailed account of this dynamic process in Dictyostelium. Centrosome behavior was monitored in living cells using a gamma-tubulin-green fluorescent protein construct and correlated with morphological changes at the ultrastructural level. All aspects of the duplication and separation process of ...

متن کامل

The centrosomal component CEP161 of Dictyostelium discoideum interacts with the Hippo signaling pathway

CEP161 is a novel component of the Dictyostelium discoideum centrosome which was identified as binding partner of the pericentriolar component CP250. Here we show that the amino acids 1-763 of the 1381 amino acids CEP161 are sufficient for CP250 binding, centrosomal targeting and centrosome association. Analysis of AX2 cells over-expressing truncated and full length CEP161 proteins revealed def...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2001